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Angiotensin II is a very potent chemical that causes the muscle surrounding the blood vessels to contract. This in turns makes the blood vessel narrow, causing an internal increase in blood pressure. Angiotensin II is a chemical that can only be produced with the help of the angiotensin converting enzyme (ACE).
Lisinopril is classified as an ACE inhibitor, and is capable of slowing down the activity of the enzyme. The number of available angiotensin II in the body decreases, thus preventing hypertension. The decrease will cause dilation of contracted blood vessels thus decreasing blood pressure. This would ease the heart’s need to forcibly pump blood, slowing progression of a possible heart failure. Likewise, this drug can also slow the progression of kidney failure. Lisinopril is commonly prescribed for patients suffering from acute myocardial infarction, heart attack, and hypertension. It can be used as maintenance medication of patients with hypertension.
One of the distinct side effects of all ACE inhibitors is the presence of a dry, persistent cough. It usually resolves after therapy. Other side effects include abdominal pain, constipation, diarrhea, rash, dizziness headache, loss of taste, loss of appetite, fainting, numbness, and tingling in the hands and feet.